Article
LIMS1 risk genotype and T cell-mediated rejection in kidney transplant recipients.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association - 9 Nov 2021
Caliskan Yasar, Karahan Gonca, Akgul Sebahat Usta, Mirioglu Safak, Ozluk Yasemin, Yazici Halil, Demir Erol, Dirim Ahmet B, Turkmen Aydin, Edwards John, Savran Fatma Oguz, Sever Mehmet S, Kiryluk Krzysztof, Gharavi Ali, Lentine Krista L
Abstract excerpt
BACKGROUND: This study aims to examine the association of LIM zinc finger domain containing 1 (LIMS1) genotype with allograft rejection in an independent kidney transplant cohort. METHODS: We genotyped 841 kidney transplant recipients for the LIMS1 rs893403 variant by Sanger sequencing followed by polymerase chain reaction confirmation of the deletion. Recipients who were homozygous for the LIMS1 rs893403...
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