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Article

DNA-lesion mapping in mammalian cells.

Methods (San Diego, Calif.) - 1 May 2009

Besaratinia Ahmad, Pfeifer Gerd P

Abstract excerpt

Formation of DNA damage is a crucial event in carcinogenesis. Irreparable DNA lesions have the potential to cause mispairing during DNA replication, thereby giving rise to mutations. Critically important mutations in cancer-related genes, i.e., oncogenes and tumor suppressor genes, are key contributors to carcinogenesis. Theoretically, co-localization(s) of persistent DNA lesions and mutational hotspots in...

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Identifiers

PMID: 19245834
DOI: 10.1016/j.ymeth.2009.02.008
PMCID: PMC2693248

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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