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Article

Membrane lipid modulations remove divalent open channel block from TRP-like and NMDA channels.

The Journal of neuroscience : the official journal of the Society for Neuroscience - 25 Feb 2009

Parnas Moshe, Katz Ben, Lev Shaya, Tzarfaty Vered, Dadon Daniela, Gordon-Shaag Ariela, Metzner Henry, Yaka Rami, Minke Baruch

Abstract excerpt

Open channel block is a process in which ions bound to the inside of a channel pore block the flow of ions through that channel. Repulsion of the blocking ions by depolarization is a known mechanism of open channel block removal. For the NMDA channel, this mechanism is necessary for channel activation and is involved in neuronal plasticity. Several types of transient receptor potential (TRP) channels, including...

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Identifiers

PMID: 19244513
DOI: 10.1523/JNEUROSCI.4280-08.2009
PMCID: PMC2672305

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CA1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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