Article
Depletion of Membrane Cholesterol Suppresses Drosophila Transient Receptor Potential-Like (TRPL) Channel Activity.
Current topics in membranes - 1 Jan 2017
Peters Maximilian, Katz Ben, Lev Shaya, Zaguri Rachel, Gutorov Rita, Minke Baruch
Abstract excerpt
Cholesterol is an essential compound of higher eukaryotic cell membranes and a known modulator of ion channel activity. Changes in phospholipids and cholesterol composition of cell membranes are known to alter the activity of ion channels. However, there is little knowledge on the effects of cholesterol on transient receptor potential (TRP) channels. In this study, we explore the effects of cholesterol depletion...
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