Article
The distribution and targeting of neuronal voltage-gated ion channels.
Nature reviews. Neuroscience - 1 Jul 2006
Lai Helen C, Jan Lily Y
Abstract excerpt
Voltage-gated ion channels have to be at the right place in the right number to endow individual neurons with their specific character. Their biophysical properties together with their spatial distribution define the signalling characteristics of a neuron. Improper channel localization could cause communication defects in a neuronal network. This review covers recent studies of mechanisms for targeting...
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