Article
Lipid raft segregation modulates TRPM8 channel activity.
The Journal of biological chemistry - 3 Apr 2009
Morenilla-Palao Cruz, Pertusa María, Meseguer Víctor, Cabedo Hugo, Viana Félix
Abstract excerpt
Transient receptor potential channels are a family of cation channels involved in diverse cellular functions. Most of these channels are expressed in the nervous system and play a key role in sensory physiology. TRPM8 (transient receptor potential melastatine 8), a member of this family, is activated by cold, cooling substances such menthol and icilin and voltage. Although TRPM8 is a thermosensitive channel...
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