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Article

Function and regulation of TRPP2 at the plasma membrane.

American journal of physiology. Renal physiology - 1 Jul 2009

Tsiokas Leonidas

Abstract excerpt

The vast majority (approximately 99%) of all known cases of autosomal dominant polycystic kidney disease (ADPKD) are caused by naturally occurring mutations in two separate, but genetically interacting, loci, pkd1 and pkd2. pkd1 encodes a large multispanning membrane protein (PKD1) of unknown function, while pkd2 encodes a protein (TRPP2, polycystin-2, or PKD2) of the transient receptor potential (TRP)...

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Topics

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Share to Calcium Signaling
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Share to PKD1 gene

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to PKD2 gene

Share to Genetic and Kidney Cyst Diseases

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Share to Polycystic Kidney, Autosomal Dominant

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Source

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Identifiers

PMID: 19244406
DOI: 10.1152/ajprenal.90277.2008
PMCID: PMC2711710

Genes

PKD1
PKD2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Function and regulation of TRPP2 at the plasma membrane.PMID 19244406Read ↗

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