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Article

Vascular polycystin proteins in health and disease.

Microcirculation (New York, N.Y. : 1994) - 1 May 2024

Mbiakop Ulrich C, Jaggar Jonathan H

Abstract excerpt

PKD1 (polycystin 1) and PKD2 (polycystin 2) are expressed in a variety of different cell types, including arterial smooth muscle and endothelial cells. PKD1 is a transmembrane domain protein with a large extracellular N-terminus that is proposed to act as a mechanosensor and receptor. PKD2 is a member of the transient receptor potential (TRP) channel superfamily which is also termed TRPP1. Mutations in the genes...

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Share to Endothelial Cells
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Polycystic Kidney, Autosomal Dominant

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Identifiers

PMID: 37823335
DOI: 10.1111/micc.12834
PMCID: PMC11009377

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