Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Submembraneous microtubule cytoskeleton: interaction of TRPP2 with the cell cytoskeleton

27 Aug 2008

Abstract excerpt

TRPP2, also called polycystin-2, the gene product of PKD2, is a membrane protein defective in 10-15% of cases of autosomal dominant polycystic kidney disease. Mutations in PKD2 are also associated with extrarenal disorders, such as hepatic cystogenesis and cardiovascular abnormalities. TRPP2 is a Ca-permeable nonselective cation channel present in the endoplasmic reticulum and plasma membrane, as well as in cilia...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Biomedical Research and Pathophysiology
Share to Genetic and Kidney Cyst Diseases
Share to Microtubule and mitosis dynamics

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 18754774
DOI: 10.1111/j.1742-4658.2008.06616.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Submembraneous microtubule cytoskeleton: interaction of TRPP2 with the cell cytoskeletonPMID 18754774Read ↗

TRP channels and kidney disease: lessons from polycystic kidney diseaseSemantic proximity Read ↗

Function and regulation of TRPP2 at the plasma membrane.Semantic proximity Read ↗

The functions of TRPP2 in the vascular system.Semantic proximity Read ↗

Polycystins and partners: proposed role in mechanosensitivity.Semantic proximity Read ↗

The TRPP subfamily and polycystin-1 proteins.Semantic proximity Read ↗

Regulation of calcium signaling by polycystin-2Semantic proximity Read ↗

Polycystin-2 cation channel function is under the control of microtubular structures in primary cilia of renal epithelial cells.Semantic proximity Read ↗

Polycystin-2 (PC2): structural insights and its role in disease pathogenesis.Semantic proximity Read ↗

The TRPM7 interactome defines a cytoskeletal complex linked to neuroblastoma progressionSemantic proximity Read ↗

Structural and molecular basis of the assembly of the TRPP2/PKD1 complexSemantic proximity Read ↗

The native TRPP2-dependent channel of murine renal primary ciliaSemantic proximity Read ↗

Regulation of PKD2 channel by TACAN: how does it link to cystogenesis in autosomal dominant polycystic kidney disease?Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.