Article
Identification and characterization of the fourth single-stranded-DNA binding domain of replication protein A.
Molecular and cellular biology - 1 Dec 1998
Brill S J, Bastin-Shanower S
Abstract excerpt
Replication protein A (RPA), the heterotrimeric single-stranded-DNA (ssDNA) binding protein (SSB) of eukaryotes, contains two homologous ssDNA binding domains (A and B) in its largest subunit, RPA1, and a third domain in its second-largest subunit, RPA2. Here we report that Saccharomyces cerevisi...
Topics
- Amino Acid Sequence
- Binding Sites
- Cell Survival
- Conserved Sequence
- Cysteine
- DNA Mutational Analysis
- DNA, Single-Stranded
- DNA-Binding Proteins
- Molecular Sequence Data
- Mutation
- Protein Conformation
- Protein Structure, Secondary
- Recombinant Proteins
- Replication Protein A
- Saccharomyces cerevisiae
- Sequence Alignment
- Viral Proteins
- Zinc