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Article

Cloning and characterization of a 3-methyladenine DNA glycosylase cDNA from human cells whose gene maps to chromosome 16.

Proceedings of the National Academy of Sciences of the United States of America - 15 Oct 1991

Samson L, Derfler B, Boosalis M, Call K

Abstract excerpt

We described previously the isolation of a Saccharomyces cerevisiae 3-methyladenine (3-MeAde) DNA glycosylase repair gene (MAG) by its expression in glycosylase-deficient Escherichia coli alkA tag mutant cells and its ability to rescue these cells from the toxic effects of alkylating agents. Here we extend this cross-species functional complementation approach to the isolation of a full-length human 3-MeAde DNA...

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Identifiers

PMID: 1924375
DOI: 10.1073/pnas.88.20.9127
PMCID: PMC52665

Genes

MAG

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Source receipt: pubmed, retrieved 7 Sept 2026.

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