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Article

Molecular cloning and genetic characterization of the Saccharomyces cerevisiae NGS1/MRE11 gene.

Current genetics - 1 Dec 1998

Chamankhah M, Xiao W

Abstract excerpt

The Saccharomyces cerevisiae ngs1-1 mutant was previously identified by its enhanced sensitivity to simple DNA-alkylating agents such as methyl methanesulfonate but not to UV. Molecular cloning and sequencing of NGS1 as a putative DNA-alkylation repair gene revealed that it isidentical to MRE11, a gene that is involved in DNA recombinational repair. In order to investigate functional domains of the Mre11 protein,...

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Source

Identifiers

PMID: 9871118
DOI: 10.1007/s002940050408

Genes

MRE11

Provenance

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Source receipt: pubmed, retrieved 7 Sept 2026.

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