Article
Molecular cloning and genetic characterization of the Saccharomyces cerevisiae NGS1/MRE11 gene.
Current genetics - 1 Dec 1998
Chamankhah M, Xiao W
Abstract excerpt
The Saccharomyces cerevisiae ngs1-1 mutant was previously identified by its enhanced sensitivity to simple DNA-alkylating agents such as methyl methanesulfonate but not to UV. Molecular cloning and sequencing of NGS1 as a putative DNA-alkylation repair gene revealed that it isidentical to MRE11,...
Topics
- Antineoplastic Agents, Alkylating
- Chromosomes, Fungal
- Cloning, Molecular
- DNA
- DNA Repair
- Endodeoxyribonucleases
- Exodeoxyribonucleases
- Fungal Proteins
- Genes, Fungal
- Methyl Methanesulfonate
- Mutation
- Recombination, Genetic
- Repetitive Sequences, Nucleic Acid
- Saccharomyces cerevisiae
- Saccharomyces cerevisiae Proteins