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Article

Intermittent calorie restriction delays prostate tumor detection and increases survival time in TRAMP mice.

Nutrition and cancer - 1 Jan 2009

Bonorden Melissa J L, Rogozina Olga P, Kluczny Christina M, Grossmann Michael E, Grambsch Patricia L, Grande Joseph P, Perkins Susan, Lokshin Anna, Cleary Margot P

Abstract excerpt

Prostate cancer is the most frequently diagnosed cancer in men. Whereas chronic calorie restriction (CCR) delays prostate tumorigenesis in some rodent models, the impact of intermittent caloric restriction (ICR) has not been determined. Here, transgenic adenocarcinoma of the mouse prostate (TRAMP) mice were used to compare how ICR and CCR affected prostate cancer development. TRAMP mice were assigned to ad...

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Identifiers

PMID: 19235043
DOI: 10.1080/01635580802419798

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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