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Article

Impact of viral selected mutations on T cell mediated immunity in chronically evolving and self limiting acute HCV infection.

Virology - 10 Apr 2009

Guglietta Silvia, Garbuglia Anna Rosa, Salichos Leonidas, Ruggeri Lionello, Folgori Antonella, Perrone Maria Paola, Camperio Cristina, Mellace Vincenzo, Maio Giuseppe, Maio Patrizia, Capobianchi Maria Rosaria, Spada Enea, Gargano Nicola, Scottà Cristiano, Piccolella Enza, Del Porto Paola

Abstract excerpt

The ability of HCV to mutate in response to cytotoxic T lymphocyte (CTL) pressure is increasingly recognized, but the influence of such a mechanism in viral persistence and final disease outcome has not been ascertained. In this study, we performed a detailed longitudinal analysis of cell mediated immunity and HCV evolution in two self limiting and two chronically evolving HCV acutely infected patients, one of...

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Share to CD8-Positive T-Lymphocytes
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to T-Lymphocytes, Cytotoxic

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Source

Identifiers

PMID: 19232664
DOI: 10.1016/j.virol.2009.01.020

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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