Article
Serum homocysteine: interplay with other circulating and genetic factors in association to Alzheimer's type dementia.
Clinical biochemistry - 1 Jun 2009
Cascalheira José F, João Sara S, Pinhanços Sandra S, Castro Rita, Palmeira Manuela, Almeida Sofia, Faria Maria C, Domingues Fernanda C
Abstract excerpt
OBJECTIVES: To study the interplay between serum concentrations of homocysteine, steroid hormones and vitamins B and mutations in 5,10-methylenetetrahydrofolate reductase (MTHFR) gene, in association to Alzheimer's type dementia (ATD). DESIGN AND METHODS: Case-control study including 19 individuals diagnosed with ATD and 36 healthy controls. Serum concentrations of the analytes were determined and MTHFR 1298A-->C...
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