Article
Alzheimer's disease in Brazilian elderly has a relation with homocysteine but not with MTHFR polymorphisms.
Arquivos de neuro-psiquiatria - 1 Dec 2006
da Silva Vanessa Cavalcante, Ramos Flávio José da Costa, Freitas Elizabete Malaquias, de Brito-Marques Paulo Roberto, Cavalcanti Márcia Nery de Holanda, D'Almeida Vânia, Cabral-Filho José Eulálio, Muniz Maria Tereza Cartaxo
Abstract excerpt
OBJECTIVE: To investigate the association between total plasma homocysteine concentration, C677T and A1298C polymorphisms in MTHFR gene and Alzheimer's disease (AD) development. METHOD: Forty-three patients with probable (63%) and possible (37%) AD and 50 non-demented controls were evaluated. Groups did not differ as to gender, age, scholar years, diabetes, alcohol and coffee intake and physical activity. Total...
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