Article
Homocysteine metabolism and cerebrospinal fluid markers for Alzheimer's disease.
Journal of Alzheimer's disease : JAD - 1 Jan 2009
Popp Julius, Lewczuk Piotr, Linnebank Michael, Cvetanovska Gabriela, Smulders Yvo, Kölsch Heike, Frommann Ingo, Kornhuber Johannes, Maier Wolfgang, Jessen Frank
Abstract excerpt
Disturbed homocysteine metabolism is a risk factor for Alzheimer's disease (AD) and may contribute to the disease pathophysiology by increasing both amyloid-beta (Abeta) production and phosphorylated tau (P-tau) accumulation. Here, we evaluated the relationship between the cerebrospinal fluid (CS...
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