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Article

Homocysteine and Alzheimer's Disease: Evidence for a Causal Link from Mendelian Randomization.

Journal of Alzheimer's disease : JAD - 22 Mar 2016

Hu Qingting, Teng Wenhui, Li Jiajia, Hao Fangfang, Wang Naidong

Abstract excerpt

BACKGROUND/OBJECTIVE: The relationship between plasma homocysteine (Hcy) levels and Alzheimer's disease (AD) has been studied for many years, but remains controversial. While a recent meta-analysis of epidemiological studies, which included observational studies, indicated that homocysteine may be a risk factor for AD, there remains a need to further demonstrate this link due to the large degree of heterogeneity...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Folate and B Vitamins Research

Share to MTHFR gene

Share to Genetic Predisposition to Disease

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Share to Methylenetetrahydrofolate Reductase (NADPH2)

Share to Polymorphism, Single Nucleotide

Source

Identifiers

PMID: 27031476
DOI: 10.3233/JAD-150977

Genes

MTHFR

Variants

rs1801133

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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