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Abnormal Homocysteine Metabolism: An Insight of Alzheimer’s Disease from DNA Methylation

8 Sept 2020

Abstract excerpt

Alzheimer's disease (AD) is a chronic neurodegenerative disease in the central nervous system that has complex pathogenesis in the elderly. The current review focuses on the epigenetic mechanisms of AD, according to the latest findings. One of the best-characterized chromatin modifications in epigenetic mechanisms is DNA methylation. Highly replicable data shows that AD occurrence is often accompanied by...

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PMID: 32963633
DOI: 10.1155/2020/8438602

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