Article
Genotype determination for polymorphisms in linkage disequilibrium.
BMC bioinformatics - 20 Feb 2009
Yu Zhaoxia, Garner Chad, Ziogas Argyrios, Anton-Culver Hoda, Schaid Daniel J
Abstract excerpt
BACKGROUND: Genome-wide association studies with single nucleotide polymorphisms (SNPs) show great promise to identify genetic determinants of complex human traits. In current analyses, genotype calling and imputation of missing genotypes are usually considered as two separated tasks. The genotyp...
Topics
- Computational Biology
- Genotype
- Linkage Disequilibrium
- Polymorphism, Single Nucleotide