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Article

Histological study in the brain of the reelin/Dab1-compound mutant mouse.

Anatomical science international - 1 Sept 2009

Yamamoto Tatsuro, Setsu Tomiyoshi, Okuyama-Yamamoto Ayako, Terashima Toshio

Abstract excerpt

The Reelin (Reln)-deficient mouse (reeler) and the Dab1-deficient mouse (yotari) are autosomal recessive mutant mice characterized by cerebellar ataxia. Previously, we reported that Reelin and Dab1 proteins have slightly different functions during the development of the cerebral cortex. To analyze the functional roles of Reelin and Dab1 proteins in detail, we attempted to generate a reelin/Dab1 compound-mutant...

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PMID: 19221860
DOI: 10.1007/s12565-008-0009-7

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