Article
Transient downregulation of Dab1 protein levels during development leads to behavioral and structural deficits: relevance for psychiatric disorders.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology - 1 Feb 2014
Teixeira Catia M, Masachs Nuria, Muhaisen Ashraf, Bosch Carles, Pérez-Martínez Javier, Howell Brian, Soriano Eduardo
Abstract excerpt
Psychiatric disorders have been hypothesized to originate during development, with genetic and environmental factors interacting in the etiology of disease. Therefore, developmentally regulated genes have received attention as risk modulators in psychiatric diseases. Reelin is an extracellular protein essential for neuronal migration and maturation during development, and its expression levels are reduced in...
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