Article
A novel neurological mutant mouse, yotari, which exhibits reeler-like phenotype but expresses CR-50 antigen/reelin.
Neuroscience research - 1 Nov 1997
Yoneshima H, Nagata E, Matsumoto M, Yamada M, Nakajima K, Miyata T, Ogawa M, Mikoshiba K
Abstract excerpt
We present yotari, a novel neurological mutant mouse whose mutation is transmitted in an autosomal recessive manner. The phenotype of yotari is very similar to that of reeler. yotari mutants are recognizable by their unstable gait and tremor and by their early deaths at around the time of weaning...
Topics
- Animals
- Antibodies, Monoclonal
- Brain
- Cell Adhesion Molecules, Neuronal
- Cerebellum
- Extracellular Matrix Proteins
- Genes, Recessive
- Genetic Complementation Test
- Mice
- Mice, Neurologic Mutants
- Nerve Tissue Proteins