Article
Association study between genes in Reelin signaling pathway and autism identifies DAB1 as a susceptibility gene in a Chinese Han population.
Progress in neuro-psychopharmacology & biological psychiatry - 1 Jul 2013
Li Jun, Liu Jing, Zhao Linnan, Ma Yuanlin, Jia Meixiang, Lu Tianlan, Ruan Yanyan, Li Qizhai, Yue Weihua, Zhang Dai, Wang Lifang
Abstract excerpt
Autism is a pervasive neurodevelopmental disorder diagnosed in early childhood. The genetic factors might play an important role in its pathogenesis. Previous studies revealed that Reelin (RELN) polymorphisms were associated with autism. However, the roles of genes in Reelin signaling pathway for autism are largely unknown. As several knockout mice models in which the Reelin pathway genes (i.e. DAB1,...
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