Article
Prognostic implications of BAX protein expression and microsatellite instability in all non-metastatic stages of primary colon cancer treated by surgery alone.
International journal of colorectal disease - 1 Jun 2009
Nehls Oliver, Hass Holger G, Okech Thomas, Zenner Silke, Hsieh Chih-Jen, Sarbia Mario, Borchard Franz, Gruenagel Hans-Helmut, Gaco Vera, Porschen Rainer, Gregor Michael, Klump Bodo
Abstract excerpt
PURPOSE: This study examined whether the apoptosis-related protein, BAX, or the microsatellite-instability phenotype provide prognostic information in patients with resected colon cancer. METHODS: A total of 371 stage I-III patients that previously underwent radical surgery were included (mean follow-up 51.8 months). BAX expression was examined by immunohistochemical staining; high-frequency microsatellite...
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