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Article

Prognostic implications of BAX and TGFBRII mutations in colon cancers with microsatellite instability.

Genes, chromosomes & cancer - 1 Dec 2002

Samowitz Wade S, Curtin Karen, Neuhausen Susan, Schaffer Donna, Slattery Martha L

Abstract excerpt

Microsatellite instability in sporadic colon cancer is associated with an improved prognosis. Recent studies, however, have suggested that microsatellite unstable cancers with mutations in the proapoptotic gene BAX have a relatively poor prognosis, whereas those with mutations in transforming growth factor-beta receptor type II (TGFBRII) have a relatively good prognosis. Using instability in the non-coding...

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Identifiers

PMID: 12378532
DOI: 10.1002/gcc.10125

Genes

BAX

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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