Article
Genetic polymorphisms in interferon pathway and response to interferon treatment in hepatitis B patients: A pilot study
1 Dec 2002
Abstract excerpt
Interferon alfa (IFN-alpha) therapy remains a mainstay of treatment in active hepatitis B. However, sustained remission rates remain relatively low, and the search for factors important for response to therapy continues. Our study aimed to identify the host single nucleotide polymorphisms (SNPs) that predict IFN response in hepatitis B patients. We selected genes in the IFN pathway involved in antiviral and...
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