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Article

Myocardin-related transcription factors and SRF are required for cytoskeletal dynamics and experimental metastasis.

Nature cell biology - 1 Mar 2009

Medjkane Souhila, Perez-Sanchez Cristina, Gaggioli Cedric, Sahai Erik, Treisman Richard

Abstract excerpt

Rho GTPases control cytoskeletal dynamics through cytoplasmic effectors and regulate transcriptional activation through myocardin-related transcription factors (MRTFs), which are co-activators for serum response factor (SRF). We used RNA interference to investigate the contribution of the MRTF-SR...

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Source

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Identifiers

PMID: 19198601
DOI: 10.1038/ncb1833
PMCID: PMC6089348

Genes

SRF
MAL
MYH9
MYL9

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19198601-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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Myocardin-related transcription factors and SRF are required for cytoskeletal dynamics and experimental metastasis.PMID 19198601Read ↗

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