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Non‐muscle myosins in tumor progression, cancer cell invasion, and metastasis

1 Aug 2014

Abstract excerpt

The actin cytoskeleton, which regulates cell polarity, adhesion, and migration, can influence cancer progression, including initial acquisition of malignant properties by normal cells, invasion of adjacent tissues, and metastasis to distant sites. Actin-dependent molecular motors, myosins, play key roles in regulating tumor progression and metastasis. In this review, we examine how non-muscle myosins regulate...

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PMID: 25087729
DOI: 10.1002/cm.21187

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