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Article

HIV-associated nephropathy: pathogenesis

23 Feb 2011

Abstract excerpt

PURPOSE OF REVIEW: HIV-associated nephropathy (HIVAN) is characterized histologically by a collapsing form of focal segmental glomerulosclerosis (FSGS), microcystic tubular dilation, interstitial inflammation and fibrosis. In this review, we provide a summary of the current state of knowledge about the mechanisms involved in the pathogenesis of HIVAN. RECENT FINDINGS: Two variants in the ApoL1 gene have been...

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PMID: 21358326
DOI: 10.1097/mnh.0b013e328345359a

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