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Article

Human immunodeficiency virus downregulates podocyte apoE expression.

American journal of physiology. Renal physiology - 1 Sept 2009

Arora Shitij, Husain Mohammad, Kumar Dileep, Patni Hitesh, Pathak Shresh, Mehrotra Devi, Reddy Vivek Kathi, Reddy Lalit Rajeev, Salhan Divya, Yadav Anju, Mathieson Peter W, Saleem Moin A, Chander Praveen N, Singhal Pravin C

Abstract excerpt

Apolipoprotein E (apoE) has been demonstrated to play an important role in providing protection against mesangial cell injury. In the present study, we evaluated the role of apoE and its associated downstream effects in human immunodeficiency virus (HIV)-associated nephropathy (HIVAN). Control (n = 6) and age- and sex-matched HIV-1 transgenic mice (Tg26, n = 6) were evaluated for their renal cortical expression...

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Share to Apolipoproteins E
Share to Cell Line, Transformed

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Down-Regulation

Share to Heparan Sulfate Proteoglycans

Share to nef Gene Products, Human Immunodeficiency Virus

Share to Podocytes

Share to Transduction, Genetic

Share to vpr Gene Products, Human Immunodeficiency Virus

Source

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Identifiers

PMID: 19553347
DOI: 10.1152/ajprenal.90668.2008
PMCID: PMC2739717

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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