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[Validation and comparison of pharmacogenetics-based warfarin dosing algorithms in Han Chinese patients].

Zhonghua xin xue guan bing za zhi - 1 Jul 2012

Yu Liang-ping, Song Hong-tao, Zeng Zhi-yong, Wang Qi-min, Qiu Han-fan

Abstract excerpt

OBJECTIVE: To assess whether the existing three types of pharmacogenetics-based Warfarin dosing algorithms appropriately predict the actual maintenance dose in Han Chinese mechanical heart valve replacement patients (n = 130). METHODS: The patients' CYP2C9 and VKORC1 genetic polymorphisms were detected by PCR-RFLP. The genotype of CYP2C9, VKORC1 and other information were used to calculate predicted doses....

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Source

Identifiers

PMID: 22943693

Genes

VKORC1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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