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Article

TRPM8.

Handbook of experimental pharmacology - 1 Jan 2014

Almaraz Laura, Manenschijn Jan-Albert, de la Peña Elvira, Viana Félix

Abstract excerpt

Transient receptor potential melastatin 8 (TRPM8) was originally cloned from prostate tissue. Shortly thereafter, the protein was identified as a cold- and menthol-activated ion channel in peripheral sensory neurons, where it plays a critical role in cold temperature detection. In this chapter, we review our current understanding of the molecular and biophysical properties, the pharmacology, and the modulation by...

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Source

Identifiers

PMID: 24756721
DOI: 10.1007/978-3-642-54215-2_22

Genes

TRPM8

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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[Transient receptor potential, TRP channels: a new family of channels broadly expressed].Semantic proximity Read ↗

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The TRP channel superfamily: insights into how structure, protein-lipid interactions and localization influence function.Semantic proximity Read ↗

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