Article
TRPV6 Regulation by Cis-22a and Cholesterol.
Biomolecules - 8 Jun 2022
Humer Christina, Lindinger Sonja, Carrel Aline L, Romanin Christoph, Höglinger Carmen
Abstract excerpt
The highly calcium-selective transient receptor potential vanilloid-type channel TRPV6 is important for epithelial Ca2+ transport. Proper regulation of the inherently constitutively active TRPV6 channels is intricate in preserving Ca2+ homeostasis, whereby structural and functional data suggest that lipids hold an essential role. Altered expression levels or specific TRPV6 mutations may lead to diseases, hence,...
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