Article
Genetics of inflammatory bowel disease: clues to pathogenesis.
British medical bulletin - 1 Jan 2008
Zhang Hu, Massey Dunecan, Tremelling Mark, Parkes Miles
Abstract excerpt
INTRODUCTION OR BACKGROUND: It has long been recognized from epidemiological data that inflammatory bowel diseases (IBD), Crohn's disease (CD) and ulcerative colitis (UC), have a strong genetic predisposition, interacting with unknown environmental drivers to render susceptible individuals at risk for relapsing intestinal inflammation. Substantial progress has been made in the last 2 years in characterizing the...
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