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Article

Tobacco and estrogen metabolic polymorphisms and risk of non-small cell lung cancer in women.

Carcinogenesis - 1 Apr 2009

Cote Michele L, Yoo Wonsuk, Wenzlaff Angela S, Prysak Geoffrey M, Santer Susan K, Claeys Gina B, Van Dyke Alison L, Land Susan J, Schwartz Ann G

Abstract excerpt

To explore the potential role for estrogen in lung cancer susceptibility, candidate single-nucleotide polymorphism (SNPs) in tobacco and estrogen metabolism genes were evaluated. Population-based cases (n = 504) included women aged 18-74, diagnosed with NSCLC in metropolitan Detroit between November 2001 and October 2005. Population-based controls (n = 527) were identified through random digit dialing and matched...

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Source

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Identifiers

PMID: 19174490
DOI: 10.1093/carcin/bgp033
PMCID: PMC2664455

Genes

XRCC1
COMT
GSTM1
GSTP1
GSTT1
NQO1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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