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Article

Distinct roles for yeast Stn1 in telomere capping and telomerase inhibition.

The EMBO journal - 3 Sept 2008

Puglisi Andrea, Bianchi Alessandro, Lemmens Laure, Damay Pascal, Shore David

Abstract excerpt

The budding yeast Cdc13, Stn1 and Ten1 (CST) proteins are proposed to function as an RPA-like complex at telomeres that protects ('caps') chromosome ends and regulates their elongation by telomerase. We show that Stn1 has a critical function in both processes through the deployment of two separable domains. The N terminus of Stn1 interacts with Ten1 and carries out its essential capping function. The C terminus...

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Identifiers

PMID: 19172739
DOI: 10.1038/emboj.2008.158
PMCID: PMC2529371

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Distinct roles for yeast Stn1 in telomere capping and telomerase inhibition.PMID 19172739Read ↗

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