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Article

BRG1 requirement for long-range interaction of a locus control region with a downstream promoter.

Proceedings of the National Academy of Sciences of the United States of America - 17 Feb 2009

Kim Shin-Il, Bultman Scott J, Kiefer Christine M, Dean Ann, Bresnick Emery H

Abstract excerpt

The dynamic packaging of DNA into chromatin is a fundamental step in the control of diverse nuclear processes. Whereas certain transcription factors and chromosomal components promote the formation of higher-order chromatin loops, the co-regulator machinery mediating loop assembly and disassembly is unknown. Using mice bearing a hypomorphic allele of the BRG1 chromatin remodeler, we demonstrate that the Brg1...

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Identifiers

PMID: 19171905
DOI: 10.1073/pnas.0806420106
PMCID: PMC2650142

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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