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Article

Significant role of estrogen and progesterone receptor sequence variants in gallbladder cancer predisposition: a multi-analytical strategy.

PloS one - 1 Jan 2012

Srivastava Anshika, Sharma Kiran Lata, Srivastava Neena, Misra Sanjeev, Mittal Balraj

Abstract excerpt

BACKGROUND: Carcinoma of gallbladder (GBC) is an aggressive malignancy. The higher incidence of gallbladder cancer in women has been partly attributed to hormonal factors. Therefore the present study was designed to explore the role of genetic variants in estrogen (ESR1, ESR2) and progesterone (PGR) receptors in conferring risk of gallbladder cancer. MATERIALS AND METHODS: The present case-control study recruited...

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Source

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Identifiers

PMID: 22808109
DOI: 10.1371/journal.pone.0040162
PMCID: PMC3393738

Genes

ESR1
ESR2
PGR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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