Article
Carcinogen Metabolism Pathway and Tumor Suppressor Gene Polymorphisms and Gallbladder Cancer Risk in North Indians: A Hospital-Based Case-Control Study.
Asian Pacific journal of cancer prevention : APJCP - 1 Dec 2019
Asai Takao, Tsuchiya Yasuo, Mishra Kumudesh, Behari Anu, Shukla Pooja, Ikoma Toshikazu, Kapoor Vinay K, Nakamura Kazutoshi
Abstract excerpt
BACKGROUND: Carcinogen metabolism pathway and tumor suppressor gene polymorphisms have been reported to be associated with increased gallbladder cancer risk. However, the association of genetic variants and gallbladder cancer risk in Indians are not well studied. We examined whether genetic polymorphisms of metabolic enzymes cytochrome P450 1A1 and glutathione S-transferase and tumor suppressor gene p53 (TP53)...
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