Polymorphisms of genes in the lipid metabolism pathway and risk of biliary tract cancers and stones: a population-based case-control study in Shanghai, China.

doi:10.1158/1055-9965.EPI-07-2704

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Polymorphisms of genes in the lipid metabolism pathway and risk of biliary tract cancers and stones: a population-based case-control study in Shanghai, China.

Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 Mar 2008

Andreotti Gabriella, Chen Jinbo, Gao Yu-Tang, Rashid Asif, Chen Bingshu E, Rosenberg Philip, Sakoda Lori C, Deng Jie, Shen Ming-Chang, Wang Bing-Sheng, Han Tian-Quan, Zhang Bai-He, Yeager Meredith, Welch Robert, Chanock Stephen, Fraumeni Joseph F, Hsing Ann W

Abstract excerpt

Biliary tract cancers, encompassing the gallbladder, extrahepatic bile duct, and ampulla of Vater, are uncommon yet highly fatal malignancies. Gallstones, the primary risk factor for biliary cancers, are linked with hyperlipidemia. We examined the associations of 12 single nucleotide polymorphisms of five genes in the lipid metabolism pathway with the risks of biliary cancers and stones in a population-based...

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PMID: 18296645
DOI: 10.1158/1055-9965.EPI-07-2704
PMCID: PMC2897750

Genes

APOB
APOE
LDLR

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