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Cholesterol metabolism gene polymorphisms and the risk of biliary tract cancers and stones: a population-based case-control study in Shanghai, China.

Carcinogenesis - 1 Jan 2011

Xu Hong-Li, Cheng Jia-Rong, Andreotti Gabriella, Gao Yu-Tang, Rashid Asif, Wang Bing-Sheng, Shen Ming-Chang, Chu Lisa W, Yu Kai, Hsing Ann W

Abstract excerpt

Biliary tract cancers are rare but fatal malignancies, with increasing incidence in Shanghai, China. Gallstones, the primary risk factor for biliary tract cancer, typically result from oversaturation of cholesterol in bile. We examined the association of five variants in three lipid metabolism-related genes (CETP, ABCG8 and LRPAP1) and biliary tract cancers and stones in a population-based case-control study in...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 21062971
DOI: 10.1093/carcin/bgq194

Genes

ABCG8
CETP
LRPAP1

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