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Article

Multi-analytic approach elucidates significant role of hormonal and hepatocanalicular transporter genetic variants in gallstone disease in North Indian population.

PloS one - 1 Jan 2013

Srivastava Anshika, Mishra Avshesh, Singh Rajan, Rai Rajani, Srivastava Neena, Mittal Balraj

Abstract excerpt

OBJECTIVE: Cholesterol gallstone disease (CGD) is a multifactorial and multistep disease. Apart from female gender and increasing age being the documented non-modifiable risk factor for gallstones the pathobiological mechanisms underlying the phenotypic expression of CGD appear to be rather complex, and one or more variations in genes could play critical roles in the diverse pathways further progressing to...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 23577061
DOI: 10.1371/journal.pone.0059173
PMCID: PMC3620121

Genes

ABCG8
ADRB3
ESR1
PGR
ESR2

Variants

rs2234693

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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