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Article

Population-specific variation in haplotype composition and heterozygosity at the POLB locus.

DNA repair - 1 May 2009

Yamtich Jennifer, Speed William C, Straka Eva, Kidd Judith R, Sweasy Joann B, Kidd Kenneth K

Abstract excerpt

DNA polymerase beta plays a central role in base excision repair (BER), which removes large numbers of endogenous DNA lesions from each cell on a daily basis. Little is currently known about germline polymorphisms within the POLB locus, making it difficult to study the association of variants at this locus with human diseases such as cancer. Yet, approximately thirty percent of human tumor types show variants of...

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Share to DNA Polymerase beta
Share to Genetics, Population

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Polymerase Chain Reaction

Share to Polymorphism, Restriction Fragment Length

Share to Polymorphism, Single Nucleotide

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Source

Open in PubMed Open full text

Identifiers

PMID: 19167932
DOI: 10.1016/j.dnarep.2008.12.005
PMCID: PMC2791466

Genes

POLB

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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