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Article

Role of genetic variation in the cannabinoid type 1 receptor gene (CNR1) in the pathophysiology of human obesity.

Pharmacogenomics - 1 May 2010

Schleinitz Dorit, Carmienke Solveig, Böttcher Yvonne, Tönjes Anke, Berndt Janin, Klöting Nora, Enigk Beate, Müller Ines, Dietrich Kerstin, Breitfeld Jana, Scholz Gerhard H, Engeli Stefan, Stumvoll Michael, Blüher Matthias, Kovacs Peter

Abstract excerpt

AIMS: The endocannabinoid system may contribute to the association of visceral fat accumulation with metabolic diseases. Here we investigated the effects of genetic variation in the cannabinoid type 1 receptor gene (CNR1) on its mRNA expression in adipose tissue from visceral and subcutaneous depots and on the development of obesity. MATERIALS & METHODS: CNR1 was sequenced in 48 nonrelated German Caucasians to...

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Source

Identifiers

PMID: 20415562
DOI: 10.2217/pgs.10.42

Genes

CNR1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Role of genetic variation in the cannabinoid type 1 receptor gene (CNR1) in the pathophysiology of human obesity.PMID 20415562Read ↗

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