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Article

Secondary replicative function of CD8+ T cells that had developed an effector phenotype.

Science (New York, N.Y.) - 23 Jan 2009

Bannard Oliver, Kraman Matthew, Fearon Douglas T

Abstract excerpt

Models of the differentiation of memory CD8+ T cells that replicate during secondary infections differ over whether such cells had acquired effector function during primary infections. We created a transgenic mouse line that permits mapping of the fate of granzyme B (gzmB)-expressing CD8+ T cells and their progeny by indelibly marking them with enhanced yellow fluorescent protein (EYFP). Virus-specific CD8+ T...

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Identifiers

PMID: 19164749
DOI: 10.1126/science.1166831
PMCID: PMC2653633

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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