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Article

Multiple layers of B cell memory with different effector functions.

Nature immunology - 1 Dec 2009

Dogan Ismail, Bertocci Barbara, Vilmont Valérie, Delbos Frédéric, Mégret Jérome, Storck Sébastien, Reynaud Claude-Agnès, Weill Jean-Claude

Abstract excerpt

Memory B cells are at the center of longstanding controversies regarding the presence of antigen for their survival and their re-engagement in germinal centers after secondary challenge. Using a new mouse model of memory B cell labeling dependent on the cytidine deaminase AID, we show that after immunization with a particulate antigen, B cell memory appeared in several subsets, comprising clusters of...

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Identifiers

PMID: 19855380
DOI: 10.1038/ni.1814

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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