Article
Mixed model segregation analysis of LDL-C concentration with genotype-covariate interaction.
Genetic epidemiology - 1 Jan 1991
Konigsberg L W, Blangero J, Kammerer C M, Mott G E
Abstract excerpt
Mixed model complex segregation analyses have in the past ignored the possibility of genotype-covariate interaction. Only in the nonmixed model with polygenic heritability equal to zero have segregation analyses been performed that allowed for genotype specific regression of the phenotype on cova...
Topics
- Animals
- Cholesterol, LDL
- Cholesterol, VLDL
- Female
- Genotype
- Male
- Models, Genetic
- Monte Carlo Method
- Papio