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Article

Glutathione provides a source of cysteine essential for intracellular multiplication of Francisella tularensis.

PLoS pathogens - 1 Jan 2009

Alkhuder Khaled, Meibom Karin L, Dubail Iharilalao, Dupuis Marion, Charbit Alain

Abstract excerpt

Francisella tularensis is a highly infectious bacterium causing the zoonotic disease tularemia. Its ability to multiply and survive in macrophages is critical for its virulence. By screening a bank of HimarFT transposon mutants of the F. tularensis live vaccine strain (LVS) to isolate intracellular growth-deficient mutants, we selected one mutant in a gene encoding a putative gamma-glutamyl transpeptidase (GGT)....

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Identifiers

PMID: 19158962
DOI: 10.1371/journal.ppat.1000284
PMCID: PMC2629122

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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