Article

Role of Thioredoxin Reductase (TrxB) in Oxidative Stress Response of <i>Francisella tularensis</i> Live Vaccine Strain

2025-04-27

Abstract excerpt

Francisella tularensis is an important human pathogen responsible for causing tularemia in the Northern Hemisphere. Francisella has been developed as a biological weapon in the past due to its extremely high virulence. F. tularensis is a Gram-negative, intracellular pathogen that primarily infects macrophages. To counteract the reactive oxygen and nitrogen species (ROS/RNS) produced by macrophages in response to...

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Literature Corpus work: 7fec1419-1e06-52f3-8fba-ab7a50d09ee2
DOI: 10.1101/2025.04.27.650861

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